Methotrexate Medicine

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Methotrexate: MedlinePlus Drug Information

(Just Now) Methotrexate is also sometimes used to treat Crohn's disease (condition in which the immune system attacks the lining of the digestive tract, causing pain, diarrhea, weight loss and fever), multiple sclerosis (MS; condition in which the immune system attacks the nerves, causing weakness, numbness, loss of muscle coordination, and problems with vision, speech, …

https://medlineplus.gov/druginfo/meds/a682019.html

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Methotrexate: Uses, Dosage, Side Effects, Warnings - …

(9 days ago) Methotrexate is a medicine that is commonly prescribed for people with rheumatoid arthritis, psoriasis, or cancer, and it can lower levels of folate (a B vitamin) in your body. You should take folic acid with methotrexate to help prevent a folate deficiency. A folate deficiency can lead to symptoms like tiredness, muscle weakness, mouth sores

https://www.drugs.com/methotrexate.html

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Methotrexate Side-effects, uses, time to work

(8 days ago) Methotrexate is a type of disease-modifying anti-rheumatic drug (DMARD).It’s used to reduce activity of the immune system for people who have certain conditions. The immune system normally protects the body from infections by causing inflammation to fight them.

https://www.versusarthritis.org/about-arthritis/treatments/drugs/methotrexate/

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Methotrexate for Arthritis Arthritis Foundation

(1 days ago) Methotrexate is widely regarded as one of the safest of all arthritis drugs, though it carries some potential downsides. Gastrointestinal symptoms such as nausea and vomiting are its most frequent side effects. Other possible side effects include hair loss, mouth sores, shortness of breath, headaches, fatigue, drowsiness and dizziness.

https://www.arthritis.org/drug-guide/medication-topics/understanding-methotrexate

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Methotrexate (Anti-Rheumatic) oral: Uses, Side Effects

(Just Now) Methotrexate has rarely caused serious (sometimes fatal) side effects. Therefore, this medication should be used only to treat cancer or severe diseases caused by an overactive immune system (such

https://www.webmd.com/drugs/2/drug-3441/methotrexate-anti-rheumatic-oral/details

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High-Alert Medications - Methotrexate - Consumer Med Safety

(5 days ago) Methotrexate is a cancer medicine. However, it is also used to treat other conditions like rheumatoid arthritis and psoriasis. It works well for these conditions if you take the medicine just once or twice a week, and in smaller doses. But if you take the medicine every day by accident, you could be harmed.

https://www.consumermedsafety.org/tools-and-resources/medication-safety-tools-and-resources/high-alert-medications/methotrexate-rheumatrex-trexal

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Managing Methotrexate for Arthritis Arthritis Foundation

(Just Now) Researchers believe that methotrexate slows the progression of RA and relieves symptoms by causing cells to release a molecule called adenosine, which blocks other chemicals that promote inflammation, explains Edwin Chan, MD, a rheumatologist and researcher at the New York University School of Medicine.

https://www.arthritis.org/health-wellness/treatment/treatment-plan/disease-management/methotrexate-managing-side-effects

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Methotrexate for Rheumatoid Arthritis (RA) Treatment: How

(8 days ago) Methotrexate for Your RA. Methotrexate is one of the most effective medications to treat rheumatoid arthritis (RA). It's the first drug most doctors prescribe after you’re diagnosed. It will

https://www.webmd.com/rheumatoid-arthritis/methotrexate-treatment-ra

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A Family Physicians' Guide to Monitoring Methotrexate

(5 days ago) Methotrexate is a toxic medication, but if it is dosed correctly and monitored appropriately, its toxic effects can be minimized.7 These effects are categorized as minor or major. Minor toxic

https://www.aafp.org/afp/2000/1001/p1607.html

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Even low-dose methotrexate can cause harm or death if

(7 days ago) Methotrexate is a medicine used to treat certain types of cancer. Doctors also prescribe methotrexate to treat other conditions such as severe rheumatoid arthritis and psoriasis (a skin condition). However, the dose and frequency of taking the medicine are different based on the condition being treated. For example, when used to treat cancer

https://www.consumermedsafety.org/medication-safety-articles/item/793-even-low-dose-methotrexate-can-cause-harm-or-death-if-taken-daily-or-with-certain-other-medicines

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Rheumatoid Arthritis Medications: List of Rheumatoid

(9 days ago) Otrexup (methotrexate) is a cytotoxic drug that also suppresses the immune system.It is used to treat psoriasis and rheumatoid arthritis.It is slightly more popular than comparable drugs. There are currently no generic alternatives for Otrexup. GoodRx has partnered with InsideRx and Antares Pharma to reduce the price for this prescription.

https://www.goodrx.com/rheumatoid-arthritis/drugs

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RA and Methotrexate: Does Methotrexate Reduce Inflammation

(9 days ago) Methotrexate Initially Not a Drug for RA. Although methotrexate has been proven as a great treatment option for RA, that isn’t why this drug was created. In fact, methotrexate was initially introduced in the 1940s as a cancer treatment drug. Doctors prescribed it to provide relief for patients with different types of cancers, such as non

https://www.rheumatoidarthritis.org/treatment/methotrexate/

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Methotrexate - Wikipedia

(2 days ago) Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune-system suppressant. It is used to treat cancer, autoimmune diseases, and ectopic pregnancy and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, gestational trophoblastic disease, and osteosarcoma. Types of …

https://en.wikipedia.org/wiki/Methotrexate

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Methotrexate Dosage Guide + Max Dose, Adjustments - Drugs.com

(6 days ago) -Pregnant women with psoriasis or rheumatoid arthritis should not receive this drug.-Methotrexate elimination is reduced in patients with impaired renal functions, ascites, or pleural effusions. Such patients require especially careful monitoring for toxicity, and require dose reduction or, in some cases, discontinuation of therapy.

https://www.drugs.com/dosage/methotrexate.html

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DBL Methotrexate Injection (Methotrexate) Drug / Medicine

(6 days ago) Methotrexate is used to treat some types of cancers. It may also be used in severe psoriasis when this condition does not improve with other medicines. This medicine

https://www.news-medical.net/drugs/DBL-Methotrexate-Injection.aspx

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methotrexate Drug Interactions - Serious Interaction - RxList

(1 days ago) Medications known to have serious interactions with methotrexate. Brand Names Include: All generic drug interactions for methotrexate (lists will include brand and generic names): 10 contraindicated drug interactions. 179 significant drug interactions. 38 minor drug interactions.

https://www.rxlist.com/drug-interactions/serious-index/methotrexate.htm

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Methotrexate-Associated Pneumonitis and Rheumatoid

(3 days ago) Introduction. Rheumatoid arthritis (RA) is the most common inflammatory arthritis with a worldwide prevalence of about 1% and a female predominance of about 3:1 ().While there are numerous synthetic and biologic disease-modifying antirheumatic drugs (DMARDs) that can halt progression of the articular manifestations of the disease, data on extraarticular …

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819370/

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methotrexate (Rheumatrex): Side Effects & Dosage

(2 days ago) Methotrexate (Rheumatrex, Trexall) is a drug prescribed to treat cancer, psoriasis, inflammatory diseases of the skin, arthritis (rheumatoid arthritis in adults and children), psoriatic arthritis, polymyositis, lupus, and to induce miscarriage in women with ectopic pregnancies.

https://www.medicinenet.com/methotrexate/article.htm

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methotrexate (Rx) - Medscape Drugs & Diseases

(1 days ago) Avoid or Use Alternate Drug. Caution should be exercised when salicylates are given in combination with methotrexate. Risk for drug interactions with methotrexate is greatest during high-dose methotrexate therapy, it has been recommended that any of these drugs be used cautiously with methotrexate even when methotrexate is used in low doses.

https://reference.medscape.com/drug/trexall-otrexup-methotrexate-343201

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Learning to Self Inject Methotrexate at Home

(1 days ago) Methotrexate comes in two forms: tablets and injections. Giving methotrexate by injection may have the following benefits: 1. The tablets may not be completely absorbed 2. The injection results in complete absorption 3. Dose adjustments are easier if you absorb all of the medication Can I inject the Methotrexate by Myself?

https://rheuminfo.com/docs/living-with-arthritis/Methotrexate-Injection-Sheet-RheumInfo.pdf

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Methotrexate Side Effects, Dosage, Uses, and More

(6 days ago) Methotrexate belongs to a class of drugs called antimetabolites. A class of drugs is a group of medications that work in a similar way. These drugs are …

https://www.healthline.com/health/methotrexate-injectable-solution

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Methotrexate: Generic, Uses, Side Effects, Dosages

(2 days ago) Methotrexate is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens, and hydatidiform mole.. In acute lymphocytic leukemia, methotrexate is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents. Methotrexate is also indicated in the …

https://www.rxlist.com/consumer_methotrexate_trexall/drugs-condition.htm

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Preventing and Managing Toxicities of High‐Dose Methotrexate

(1 days ago) Introduction. Methotrexate is an antimetabolite that interferes with the metabolism of folic acid. After entry into the cell, methotrexate is polyglutamated, binds dihydrofolate reductase (DHFR) with an affinity 1,000-fold greater than that of folate, and competitively inhibits conversion of dihydrofolate to tetrahydrofolate ().Tetrahydrofolate is essential for biosynthesis …

https://theoncologist.onlinelibrary.wiley.com/doi/10.1634/theoncologist.2015-0164

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Methotrexate - Medications for Rheumatoid Arthritis (RA)

(9 days ago) 10491. Advertisment. Methotrexate (mtx) is the current ‘gold standard’ of Rheumatoid Arthritis treatment. While it comes with a whole host of unpleasant side effects, it has the highest rate of continued long-term treatment. In short, the side effects are worth it to most people, because it reduces their joint pain and inflammation effectively.

https://www.arthriticchick.com/medications/dmards/medications-for-rheumatoid-arthritis-methotrexate

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Methotrexate (Otrexup, Rasuvo, Rheumatrex, Trexall

(2 days ago) Drug type: Methotrexate is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This medication is classified as an "antimetabolite." (For more detail, see "How this drug works" section below). What Methotrexate Is Used For: Acute lymphoblastic leukemia (ALL)

https://chemocare.com/chemotherapy/drug-info/Methotrexate.aspx

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Methotrexate - StatPearls - NCBI Bookshelf

(5 days ago) Methotrexate (MTX) is an anti-metabolite most commonly used in chemotherapy and immunosuppressant in auto-immune diseases. This activity describes the indications, action, and contraindications for Methotrexate as a valuable agent in treating a wide variety of neoplastic diseases. This activity will highlight the mechanism of action, adverse event profile, and other …

https://www.ncbi.nlm.nih.gov/books/NBK556114/

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METHOTREXATE TABLETS, USP - Food and Drug Administration

(5 days ago) methotrexate, may occur in patients receiving low-dose methotrexate and, thus, may not require cytotoxic treatment. Discontinue metho-trexate first and, if the lymphoma does not regress, appropriate treatment should be instituted. 8. Like other cytotoxic drugs, methotrexate may induce “tumor lysis syndrome” in patients with rapidly growing

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/008085s066lbl.pdf

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Guidelines to Help Reduce the Side-Effects of Methotrexate

(8 days ago) Methotrexate (also sold under the brand names Rheumatrex and Trexall) is an immunosuppressant drug often prescribed for people with inflammatory types of arthritis. Many patients on methotrexate have few or no side-effects. Among those who do have problems, most side-effects resolve by lowering the dose or, if needed, discontinuation of the drug.

https://www.hss.edu/conditions_guidelines-reduce-side-effects-methotrexate.asp

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Molecular action of methotrexate in inflammatory diseases

(7 days ago) Methotrexate was first developed in the 1940s as a specific antagonist of folic acid. This drug inhibits the proliferation of malignant cells, primarily by inhibiting the de novo synthesis of purines and pyrimidines. Because administration of high doses of reduced folic acid (folinic acid) or even folic acid itself can reverse the antiproliferative effects of methotrexate, it …

https://arthritis-research.biomedcentral.com/articles/10.1186/ar419

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Leucovorin with high dose methotrexate (HDMTX) - St. Jude

(2 days ago) High-dose methotrexate (HDMTX) is an anticancer medicine. It is a clear yellow liquid given by vein (IV). Leucovorin is sometimes called a “rescue” medicine. It is taken in an effort to “rescue” the normal cells in the body from the side effects of methotrexate. Leucovorin is …

https://www.stjude.org/treatment/patient-resources/caregiver-resources/medicines/a-z-list-of-medicines/leucovorin-with-high-dose-methotrexate-hdmtx.html

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Methotrexate C20H22N8O5 - PubChem

(4 days ago) Methotrexate C20H22N8O5 - PubChem. National Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. National Library of Medicine. National Institutes of Health. Department of Health and Human Services.

https://pubchem.ncbi.nlm.nih.gov/compound/methotrexate

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Methotrexate Treatment for Psoriasis: National Psoriasis

(9 days ago) Methotrexate can cause a reduced white blood cell count, increasing infection risk. Individuals taking methotrexate must have regular blood tests to ensure that the drug is safely processed by the body including the liver, white blood cells and bone marrow. Additional tests are needed at regular intervals.

https://www.psoriasis.org/methotrexate/

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Discovery – Methotrexate: Chemotherapy Treatment for

(3 days ago) Turning Discovery into Health. In the 1950s and 1960s, the use of methotrexate was just beginning to be explored. It would soon prove useful in treating breast cancer, head and neck cancer, and osteogenic sarcoma (a bone cancer), either alone or in combination with other chemotherapy drugs. The field of medical oncology exploded in the 1960s

https://www.cancer.gov/research/progress/discovery/methotrexate

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Methotrexate Cancer information Cancer Research UK

(3 days ago) Methotrexate is one of a group of chemotherapy drugs called anti metabolites. These stop cells making and repairing DNA. Cancer cells need to make and repair DNA so that they can grow and multiply. Methotrexate stops the cells working properly. Methotrexate also stops some normal cells working properly, causing side effects.

https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/methotrexate-maxtrex

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Methotrexate - St. Jude Children’s Research Hospital

(Just Now) Methotrexate (also called MTX) is an anticancer medicine. It is available as a 2.5 mg, 5 mg, and 15 mg tablet and an oral liquid to be taken by mouth. It is also available as a yellow liquid given by vein (IV) or injected into a muscle. Methotrexate can pose a health hazard to caregivers. All caregivers should take safety precautions while

https://www.stjude.org/treatment/patient-resources/caregiver-resources/medicines/a-z-list-of-medicines/methotrexate.html

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Find Top Doctors who treat Rheumatoid Arthritis in Pine

(Just Now) What is Rheumatoid Arthritis? Rheumatoid arthritis is an autoimmune inflammation of the joints and other organs in the body. Typically this condition causes progressive changes and destruction of the affected joints, leading to impaired joint function …

https://doctor.webmd.com/find-a-doctor/condition/rheumatoid-arthritis/new-york/pine-plains

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Do Some Arthritis, IBD Drugs Put Patients at Greater COVID

(6 days ago) Methotrexate monotherapy was most common among patients in the GRA registry, at 42%, the authors noted. A total of 1,297 patients (21%) were hospitalized and 189 (3%) died from COVID-19

https://www.medpagetoday.com/gastroenterology/inflammatoryboweldisease/95105

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Methotrexate for Psoriatic Arthritis: Benefits, Side

(6 days ago) Overview. Methotrexate (MTX) is a drug that’s been used to treat psoriatic arthritis for more than 50 years.Alone or in combination with other therapies, MTX is considered a first-line treatment

https://www.healthline.com/health/psoriatic-arthritis/methotrexate

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Find Top Doctors who treat Rheumatoid Arthritis and accept

(4 days ago) What is Rheumatoid Arthritis? Rheumatoid arthritis is an autoimmune inflammation of the joints and other organs in the body. Typically this condition causes progressive changes and destruction of the affected joints, leading to impaired joint function …

https://doctor.webmd.com/find-a-doctor/condition/rheumatoid-arthritis/new-york/rhinebeck/fidelis-care-ny-state-of-health-hbx

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